Recombinant Human APP Protein, Fc tag
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产品编号
KMH507
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别名
AAA, AD1, PN2, ABPP, APPI, CVAP, ABETA, PN II, preA4, CTFgamma, amyloid beta precursor protein
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规格
- 50ug
- 100ug
Alias | AAA, AD1, PN2, ABPP, APPI, CVAP, ABETA, PN II, preA4, CTFgamma, amyloid beta precursor protein |
Catalog Number | KMH507 |
Molecular Name | APP |
Species | Human |
Host | Mammalian cells |
Size | 50ug, 100ug |
Protein Family | Antibody drug target protein |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Formulation | PBS |
Background | This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP6 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 98.59 kDa |
Note | 仅供科研使用 |