Recombinant Human ERBB3 Protein, His Tag_天津卡梅德科技发展有限公司

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Recombinant Human ERBB3 Protein, His Tag

Recombinant Human ERBB3 Protein, His Tag

产品编号

KMH505

别名

HER3, FERLK, LCCS2, ErbB 3, c erbB3, erbB3 S, MDA BF 1, c erbB 3, p180 ErbB3, p45 sErbB3, p85 sErbB3, erb b2 receptor tyrosine kinase 3

规格

50ug
100ug

DATASHEET MSDS

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产品介绍

Alias	HER3, FERLK, LCCS2, ErbB 3, c erbB3, erbB3 S, MDA BF 1, c erbB 3, p180 ErbB3, p45 sErbB3, p85 sErbB3, erb b2 receptor tyrosine kinase 3
Catalog Number	KMH505
Molecular Name	ERBB3
Species	Human
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	Antibody drug target protein
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	ErbB3, also called Her3 (human epidermal growth factor receptor 3), is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB family members serve as receptors for the epidermal growth factor (EGF) family of growth factors. Among ErbB family members, ErbB3 is unique in that it contains a defective kinase domain. ErbB3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric ErbB3 serves as a low affinity receptor for the heregulins (HRG). ErbB3 can induce specific antibody production in vivo, hence to inhibit tumor cell growth. ErbB-3 can be used to treat early, medium and advanced or post-operative breast cancer with over-expression of ErbB2. According to its mechanism of action, ErbB3 is classified as a therapeutic for cancer.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	70.73 kDa
Note	仅供科研使用

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