Recombinant Human C5 Protein, No Tag
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产品编号
KMH497
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别名
C5D, C5a, C5b, ECLZB, CPAMD4, complement C5
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规格
- 50ug
- 100ug
Alias | C5D, C5a, C5b, ECLZB, CPAMD4, complement C5 |
Catalog Number | KMH497 |
Molecular Name | C5 |
Species | Human |
Host | E. coli |
Size | 50ug, 100ug |
Protein Family | Antibody drug target protein |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | Please contact our customer service for more information. |
Formulation | PBS |
Background | The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to a susceptibility to liver fibrosis and to rheumatoid arthritis. |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 8.14 kDa |
Note | 仅供科研使用 |