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Recombinant Human C5 Protein, No Tag

Recombinant Human C5 Protein, No Tag

产品编号

KMH497

别名

C5D, C5a, C5b, ECLZB, CPAMD4, complement C5

规格
  • 50ug
  • 100ug
产品介绍
AliasC5D, C5a, C5b, ECLZB, CPAMD4, complement C5
Catalog NumberKMH497
Molecular NameC5
SpeciesHuman
HostE. coli
Size50ug, 100ug
Protein FamilyAntibody drug target protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
EndotoxinPlease contact our customer service for more information.
FormulationPBS
BackgroundThe protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to a susceptibility to liver fibrosis and to rheumatoid arthritis.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight8.14 kDa
Note仅供科研使用

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