Recombinant Human CD358/TNFRSF21 Protein, His Tag
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产品编号
KMH490
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别名
DR6, CD358, BM 018, TNF receptor superfamily member 21
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规格
- 50ug
- 100ug
Alias | DR6, CD358, BM 018, TNF receptor superfamily member 21 |
Catalog Number | KMH490 |
Molecular Name | TNFRSF21 |
Species | Human |
Host | Mammalian cells |
Size | 50ug, 100ug |
Protein Family | CD molecule |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Formulation | PBS |
Background | Death receptor-6 (DR6), a member of the death domain-containing TNFR superfamily, is highly expressed in lymphoid tissues and regulated upon lymphocyte activation. Targeted disruption of DR6 results in enhanced CD4(+) T cell proliferation and T helper 2 differentiation in vitro. DR6 contains an extracellular region and an intracellular region, the intracellular region harbors a death domain that is critical for transduction of apoptotic signals. DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-κB and JNK. |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 38.5 kDa |
Note | 仅供科研使用 |