Recombinant Human CD357/TNFRSF18 Protein, His Tag
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产品编号
KMH489
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别名
AITR, GITR, CD357, GITR D, ENERGEN, TNF receptor superfamily member 18
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规格
- 50ug
- 100ug
| Alias | AITR, GITR, CD357, GITR D, ENERGEN, TNF receptor superfamily member 18 |
| Catalog Number | KMH489 |
| Molecular Name | TNFRSF18 |
| Species | Human |
| Host | Mammalian cells |
| Size | 50ug, 100ug |
| Protein Family | CD molecule |
| Purity | ≥90% as determined by SDS-PAGE |
| Purification | Affinity Purification |
| Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
| Formulation | PBS |
| Background | GITR (glucocorticoid-induced tumor necrosis factor receptor) also known as TNFRSF18, is a surface receptor molecule that has been shown to be involved in inhibiting the suppressive activity of T-regulatory cells and extending the survival of T-effector cells.1 GITR is involved in the regulation of T-cell receptor mediated cell death. Constitutive expression of a transfected GITR gene induces resistance to apoptosis induced by anti CD3 monoclonal antibodies. GITR ligand interferes with the suppressor activity of CD4(+) CD25(+) regulatory T-cells. |
| Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Molecular Weight | 17.71 kDa |
| Note | 仅供科研使用 |
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