Recombinant Human CD321/F11R Protein, His Tag_天津卡梅德科技发展有限公司

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Recombinant Human CD321/F11R Protein, His Tag

Recombinant Human CD321/F11R Protein, His Tag

产品编号

KMH464

别名

JAM, KAT, JAM1, JAMA, JCAM, CD321, PAM 1, F11 receptor

规格

50ug
100ug

DATASHEET MSDS

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产品介绍

Alias	JAM, KAT, JAM1, JAMA, JCAM, CD321, PAM 1, F11 receptor
Catalog Number	KMH464
Molecular Name	F11R
Species	Human
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	CD molecule
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	As a typeⅠtransmembrane receptor belonging to the immunoglobulin superfamily, the human JAM-A, also known as platelet adhesion molecule 1(PAM-1) and platelet F11 receptor, is the firstly identified member of the Junctional Adhesion Molecule (JAM) family comprising at least three members. JAM-A is specifically localized in tight junctions of epithelial and endothelial cells and is involved in the regulation of junctional integrity and permeability by serving as a physical barrier in a homophilic manner. JAM-A is also expressed on the surface of hematopoeitic cells, such as platelets and leukocytes, and acts as a ligand for integrin LFA-1 or a platelet receptor, consequently plays key roles in a variety of cellular processes, including platelet aggregation, leukocyte transmigration, and angiogenesis. In addition, JAM-A has also been implicated in the attachment of reovirus that causes diarrhea in human.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	26.62 kDa
Note	仅供科研使用

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