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Recombinant Human CD309/KDR Protein, His Tag

Recombinant Human CD309/KDR Protein, His Tag

产品编号

KMH456

别名

FLK1, CD309, VEGFR, VEGFR2, kinase insert domain receptor

规格
  • 50ug
  • 100ug
产品介绍
AliasFLK1, CD309, VEGFR, VEGFR2, kinase insert domain receptor
Catalog NumberKMH456
Molecular NameKDR
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyCD molecule
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundKDR (or kinase insert domain receptor) is a growth factor receptor tyrosine kinase that was originally isolated from human endothelial cells where it plays a pivotal role in endothelial cell proliferation and differentiation. KDR and its mouse homolog Flk1 bind VEGF with high affinity and are implicated in the development of new blood vessels (angiogenesis). The expression levels of VEGF and KDR are highly correlated during the normal development of the ocular vasculature in humans (1). Induction of angiogenesis is a critical step in tumor progression, and inhibitors of KDR have been demonstrated both to induce tumor regression and reduce metastatic potential in preclinical models.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight35.97 kDa
Note仅供科研使用

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