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Recombinant Human CD289/TLR9 Protein, His Tag

Recombinant Human CD289/TLR9 Protein, His Tag

产品编号

KMH436

别名

CD289, toll like receptor 9

规格
  • 50ug
  • 100ug
产品介绍
AliasCD289, toll like receptor 9
Catalog NumberKMH436
Molecular NameTLR9
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyCD molecule
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundThe protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural andfunctional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylatedCpG dinucleotides in bacterial DNA to mount an innate immune response.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight89.98 kDa
Note仅供科研使用

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