Recombinant Human CD220/INSR Protein, His Tag_天津卡梅德科技发展有限公司

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Recombinant Human CD220/INSR Protein, His Tag

Recombinant Human CD220/INSR Protein, His Tag

产品编号

KMH382

别名

HHF5, CD220, insulin receptor

规格

50ug
100ug

DATASHEET MSDS

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产品介绍

Alias	HHF5, CD220, insulin receptor
Catalog Number	KMH382
Molecular Name	INSR
Species	Human
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	CD molecule
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	InsR is the insulin receptor tyrosine kinase that is involved in insulin signaling. InsR is post-translationally cleaved into two chains, α and β that are covalently linked. Binding of insulin to the InsR stimulates glucose uptake. Insulin receptor signaling helps to maintain fuel homeostasis and prevent diabetes. Studies have shown that a conditional knockout of insulin receptor substrate 2 (IRS2) in mouse pancreas β cells and parts of the brain-including the hypothalamus-increased appetite, lean and fat body mass, linear growth, and insulin resistance that progressed to diabetes. InsR signaling also increases the regeneration of adult β cells and the central control of nutrient homeostasis.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	83.38 kDa
Note	仅供科研使用

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