Recombinant Human CD218A/IL18R1 Protein, His Tag
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产品编号
KMH380
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别名
IL18RA, IL1RRP, CDw218a, IL 1Rrp, IL 18Ralpha, IL18Ralpha2, IL 18R alpha, interleukin 18 receptor 1
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规格
- 50ug
- 100ug
Alias | IL18RA, IL1RRP, CDw218a, IL 1Rrp, IL 18Ralpha, IL18Ralpha2, IL 18R alpha, interleukin 18 receptor 1 |
Catalog Number | KMH380 |
Molecular Name | IL18R1 |
Species | Human |
Host | Mammalian cells |
Size | 50ug, 100ug |
Protein Family | CD molecule |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Formulation | PBS |
Background | The interleukin-18 receptor 1 (IL-18R1) is a cytokine receptor of the immunoglobulin superfamily. IL18R1 is also known as IL-18Rα, CDw218a (cluster of differentiation w218a), IL-1Rrp, and IL-1R family member. IL-18R1 specifically binds to interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IL-18Rα is expressed on Th1 cells, NK cell subset, neutrophils and IL-12-stimulated tonsillar B cells. By itself, IL-18Rα binds IL-18 with low affinity and when complexed with IL-18Rβ chain binds IL-18 with high affinity. The proinflammatory cytokine IL-18 and its receptor complex play an important role in the innate and autoimmune responses. |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 36.19 kDa |
Note | 仅供科研使用 |