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Recombinant Human CD218A/IL18R1 Protein, His Tag

Recombinant Human CD218A/IL18R1 Protein, His Tag

产品编号

KMH380

别名

IL18RA, IL1RRP, CDw218a, IL 1Rrp, IL 18Ralpha, IL18Ralpha2, IL 18R alpha, interleukin 18 receptor 1

规格
  • 50ug
  • 100ug
产品介绍
AliasIL18RA, IL1RRP, CDw218a, IL 1Rrp, IL 18Ralpha, IL18Ralpha2, IL 18R alpha, interleukin 18 receptor 1
Catalog NumberKMH380
Molecular NameIL18R1
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyCD molecule
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundThe interleukin-18 receptor 1 (IL-18R1) is a cytokine receptor of the immunoglobulin superfamily. IL18R1 is also known as IL-18Rα, CDw218a (cluster of differentiation w218a), IL-1Rrp, and IL-1R family member. IL-18R1 specifically binds to interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IL-18Rα is expressed on Th1 cells, NK cell subset, neutrophils and IL-12-stimulated tonsillar B cells. By itself, IL-18Rα binds IL-18 with low affinity and when complexed with IL-18Rβ chain binds IL-18 with high affinity. The proinflammatory cytokine IL-18 and its receptor complex play an important role in the innate and autoimmune responses.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight36.19 kDa
Note仅供科研使用

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