Recombinant Human CD213A2/IL13RA2 Protein, Fc Tag
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产品编号
KMH378
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别名
CT19, IL 13R, IL13BP, CD213A2, interleukin 13 receptor subunit alpha 2
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规格
- 50ug
- 100ug
Alias | CT19, IL 13R, IL13BP, CD213A2, interleukin 13 receptor subunit alpha 2 |
Catalog Number | KMH378 |
Molecular Name | IL13RA2 |
Species | Human |
Host | Mammalian cells |
Size | 50ug, 100ug |
Protein Family | CD molecule |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Formulation | PBS |
Background | Interleukin 13 receptor alpha 2, also known as IL13RA2 and CD213A2, binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. IL13RA2 serves as a dominant negative inhibitor or a decoy receptor for IL-13. IL-13Ralpha2 is a promising target for ovarian cancer therapy, and the soluble form of IL-13R may be a possible surrogate marker for disease monitoring. IL13RA2 signaling during prolonged inflammation is also an important therapeutic target for the prevention of TGF-beta(1)-mediated fibrosis. |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 62.62 kDa |
Note | 仅供科研使用 |