| Alias | CRFB4, CRF2 4, D21S58, D21S66, CDW210B, IL 10R2, interleukin 10 receptor subunit beta |
| Catalog Number | KMH375 |
| Molecular Name | IL10RB |
| Species | Human |
| Host | Mammalian cells |
| Size | 50ug, 100ug |
| Protein Family | CD molecule |
| Purity | ≥90% as determined by SDS-PAGE |
| Purification | Affinity Purification |
| Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
| Formulation | PBS |
| Background | The functional IL-1 receptor consists of two polypeptide chains, a ligand binding chain IL-1 Rα (IL-1 R1) and a signal transduction molecule known as IL-1 Rβ (IL-1 R2). Both chains of the IL-1 R are expressed on many hematopoietic cells, including lymphocytes, monocytes and neutrophils, with the IL-1 Rβ chain expressed at higher levels than the IL-1 Rα chain in most cases. Interleukin 1 receptor beta (IL-1 Rβ), also known as CD21b and CRF2-4, is an 8-85 kDa member of the type II cytokine receptor family of proteins and contains two fibronectin type-III domains. The widely expressed IL-1 Rβ serves as a signal transducing accessory chain not only for IL-1, but also for other interleukins including IL-22, -28A, -28B and -29 (plus IL-26 in human) when complexed to the ligand-binding chains. |
| Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Molecular Weight | 24.2 kDa |
| Note | 仅供科研使用 |
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