Recombinant Human CD209 Protein, Fc Tag_天津卡梅德科技发展有限公司

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Recombinant Human CD209 Protein, Fc Tag

Recombinant Human CD209 Protein, Fc Tag

产品编号

KMH373

别名

CDSIGN, CLEC4L, DC SIGN, DC SIGN1, CD209 molecule

规格

50ug
100ug

DATASHEET MSDS

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产品介绍

Alias	CDSIGN, CLEC4L, DC SIGN, DC SIGN1, CD209 molecule
Catalog Number	KMH373
Molecular Name	CD209
Species	Human
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	CD molecule
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	Human Dendritic Cell-specific ICAM-3 Grabbing Non-integrin (DC-SIGN)/CD29 is a member of the C-type lectin family. The canonical DC-SIGN/CD29 isoform is a 46 kDa, 44 amino acid (aa) type II transmembrane protein. The extracellular region contains a Ca2+-dependent carbohydrate-binding lectin domain. Multiple human DC-SIGN/CD29 splice forms exist, generating both membrane-bound and soluble forms. DC-SIGN/CD29 is not well conserved between mouse and human, with the extracellular domain sharing only 63% aa identity. The DC-SIGN/CD29 lectin domain binds mannose oligosaccharides on pathogens including HIV as well as self glycoproteins including ICAMs. DC-SIGN/CD29 binds to butyrophilin 2A1 and this interaction can be blocked by HIV pp12. DC-SIGN/CD29 is expressed on dendritic cells (DC) and inflammatory macrophages and contributes to antigen presentation.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	63.06 kDa
Note	仅供科研使用

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