Recombinant Human CD178/FASLG Protein, His Tag
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产品编号
KMH360
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别名
APTL, FASL, CD178, CD95L, ALPS1B, CD95 L, TNFSF6, TNLG1A, APT1LG1, Fas ligand
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规格
- 50ug
- 100ug
Alias | APTL, FASL, CD178, CD95L, ALPS1B, CD95 L, TNFSF6, TNLG1A, APT1LG1, Fas ligand |
Catalog Number | KMH360 |
Molecular Name | FASLG |
Species | Human |
Host | Mammalian cells |
Size | 50ug, 100ug |
Protein Family | CD molecule |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Formulation | PBS |
Background | Fas ligand (FasL) is a type II transmembrane protein that belongs to the tumor necrosis factor (TNF) family. Fas ligand is a homotrimeric protein and signals through trimerization of FasR, which spans the membrane of the target cell. This trimerization usually leads to apoptosis, or cell death. Soluble Fas ligand is generated by cleaving membrane-bound FasL at a conserved cleavage site by the external serine matrix metalloproteinase MMP-7. Soluble FasL is less active than their membrane-bound counterparts and do not induce receptor trimerization and DISC formation. FasL is regarded as a potential target for immunotherapy. |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 16.28 kDa |
Note | 仅供科研使用 |