| Alias | CD153, CD30L, CD30LG, TNLG3A, TNF superfamily member 8 |
| Catalog Number | KMH326 |
| Molecular Name | TNFSF8 |
| Species | Human |
| Host | Mammalian cells |
| Size | 50ug, 100ug |
| Protein Family | CD molecule |
| Purity | ≥90% as determined by SDS-PAGE |
| Purification | Affinity Purification |
| Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
| Formulation | PBS |
| Background | The CD3 ligand is a type II transmembrane glycoprotein of the tumor necrosis factor ligand superfamily. CD3L is expressed on the cell surface of activated T cells, B cells, and monocytes. Recombinant CD3L has been shown to co-stimulate T cells and to act as a mitogen for Hodgkin"s disease derived cell lines. The receptor for CD3L, CD3/TNFRSF8/CD153, is a type I cytokine receptor that is highly expressed by activated T cells, Hodgkin and Reed- Sternberg (H-RS) cells, and anaplastic large cell lymphoma cells. CD3 ligation by CD3L mediates pleiotropic effects including cell proliferation, activation, differentiation and cell death by apoptosis. |
| Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Molecular Weight | 43.92 kDa |
| Note | 仅供科研使用 |
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