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Recombinant Human CD134/TNFRSF4 Protein, His Tag

Recombinant Human CD134/TNFRSF4 Protein, His Tag

产品编号

KMH310

别名

OX40, ACT35, CD134, IMD16, TXGP1L, TNF receptor superfamily member 4

规格
  • 50ug
  • 100ug
产品介绍
AliasOX40, ACT35, CD134, IMD16, TXGP1L, TNF receptor superfamily member 4
Catalog NumberKMH310
Molecular NameTNFRSF4
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyCD molecule
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundOX4L, a member of the TNF superfamily of structurally related proteins, exists primarily as a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells (APCs), such as dendritic cells and activated B-cells, and also on various other cells such as vascular endothelial cells, mast cells, and natural killer cells. OX4L signals specifically through the OX4 receptor, which is expressed predominantly on CD4+T cells but also on certain activated CD8+T cells. OX4/OX4L functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival, and increases expression of RANTES, IL-2, IL-3, and IFN&gamma.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight23.76 kDa
Note仅供科研使用

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