Recombinant Human CD134/TNFRSF4 Protein, His Tag
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产品编号
KMH310
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别名
OX40, ACT35, CD134, IMD16, TXGP1L, TNF receptor superfamily member 4
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规格
- 50ug
- 100ug
Alias | OX40, ACT35, CD134, IMD16, TXGP1L, TNF receptor superfamily member 4 |
Catalog Number | KMH310 |
Molecular Name | TNFRSF4 |
Species | Human |
Host | Mammalian cells |
Size | 50ug, 100ug |
Protein Family | CD molecule |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Formulation | PBS |
Background | OX4L, a member of the TNF superfamily of structurally related proteins, exists primarily as a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells (APCs), such as dendritic cells and activated B-cells, and also on various other cells such as vascular endothelial cells, mast cells, and natural killer cells. OX4L signals specifically through the OX4 receptor, which is expressed predominantly on CD4+T cells but also on certain activated CD8+T cells. OX4/OX4L functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival, and increases expression of RANTES, IL-2, IL-3, and IFN&gamma. |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 23.76 kDa |
Note | 仅供科研使用 |