Recombinant Human CD115/CSF1R Protein, His Tag
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产品编号
KMH290
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别名
FMS, CSFR, FIM2, HDLS, C FMS, CD115, CSF 1R, BANDDOS, M CSF R, colony stimulating factor 1 receptor
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规格
- 50ug
- 100ug
产品介绍
| Alias | FMS, CSFR, FIM2, HDLS, C FMS, CD115, CSF 1R, BANDDOS, M CSF R, colony stimulating factor 1 receptor |
| Catalog Number | KMH290 |
| Molecular Name | CSF1R |
| Species | Human |
| Host | Mammalian cells |
| Size | 50ug, 100ug |
| Protein Family | CD molecule |
| Purity | ≥90% as determined by SDS-PAGE |
| Purification | Affinity Purification |
| Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
| Formulation | PBS |
| Background | Macrophage colony-stimulating factor (M-CSF, also termed CSF-1) receptor is an integral membrane tyrosine kinase, expressed in monocytes (macrophages and their progenitors) and drives growth and development of this blood cell lineage. It also triggers growth and development of mononuclear phagocytes and placental trophoblasts. M-CSF receptor is present in osteoclasts both at mRNA and protein levels. When M-CSF ligand specifically binds to the M-CSF receptor on osteoclasts, it induces receptor dimerization, activation and autophosphorylation of cytoplasmic tyrosine residues M-CSF and its receptor present as candidate therapeutic targets in states of inflammatory bone erosion. |
| Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Molecular Weight | 56.32 kDa |
| Note | 仅供科研使用 |
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