Recombinant Human CD86 Protein, His Tag
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产品编号
KMH261
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别名
B70, B7 2, B7.2, LAB72, CD28LG2, CD86 molecule [ Homo sapiens
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规格
- 50ug
- 100ug
| Alias | B70, B7 2, B7.2, LAB72, CD28LG2, CD86 molecule [ Homo sapiens |
| Catalog Number | KMH261 |
| Molecular Name | CD86 |
| Species | Human |
| Host | Mammalian cells |
| Size | 50ug, 100ug |
| Protein Family | CD molecule |
| Purity | ≥90% as determined by SDS-PAGE |
| Purification | Affinity Purification |
| Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
| Formulation | PBS, pH7.5 |
| Background | B7-1 and B7-2, together with their receptors CD28 and CTLA-4, constitute one of the dominant costimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 2 - 1 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells. |
| Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Molecular Weight | 28.92 kDa |
| Note | 仅供科研使用 |
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