Recombinant Human CD83 Protein, His Tag_天津卡梅德科技发展有限公司

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Recombinant Human CD83 Protein, His Tag

Recombinant Human CD83 Protein, His Tag

产品编号

KMH248

别名

BL11, HB15, CD83 molecule

规格

50ug
100ug

DATASHEET MSDS

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产品介绍

Alias	BL11, HB15, CD83 molecule
Catalog Number	KMH248
Molecular Name	CD83
Species	Human
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	CD molecule
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS, pH7.5
Background	Human CD83 is a 4-5 kDa member of the Siglec (or sialic-acid-binding immunoglobulin-like lectin) family of transmembrane proteins. CD83 is a primary marker for dendritic cells. It is also found on B cells, neutrophils, monocytes and macrophages. Except for dendritic cells, CD83 expression is often transient. CD83 binds to sialic acids on target cells. Membrane CD83 promotes T cell proliferation, particularly of CD8+ cytotoxic T cells. Soluble CD83 is immunosuppressive and blocks T cell activation. On monocytes, CD83 is suggested to drive monocytes into a fibrocyte phenotype. A lack of membrane-expressed CD83 leads to an unusual IL-4/IL-1 producing CD4+ T cell phenotype.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	15.73 kDa
Note	仅供科研使用

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