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Recombinant Human CD62P/SELP Protein, His Tag

Recombinant Human CD62P/SELP Protein, His Tag

产品编号

KMH226

别名

CD62, GRMP, PSEL, GMP140, LECAM3, PADGEM, selectin P

规格
  • 50ug
  • 100ug
产品介绍
AliasCD62, GRMP, PSEL, GMP140, LECAM3, PADGEM, selectin P
Catalog NumberKMH226
Molecular NameSELP
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyCD molecule
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundPlasma Selectin (P-selectin) is a cell adhesion molecule (CAM) found in granules in endothelial cells (cells lining blood vessels) and activated platelets. P-Selectin is expressed on activated endothelium and platelets where it can bind monocytes, neutrophils, stimulated T cells, and platelets. P-selectin plays an essential role in the initial recruitment of leukocytes (white blood cells) to the site of injury during inflammation. When endothelial cells are activated by molecules such as histamine or thrombin during inflammation, P-selectin moves from an internal cell location to the endothelial cell surface. Thrombin is one trigger which can stimulate endothelial-cell release of P-selectin and recent studies suggest an additional Ca2+-independent pathway involved in release of P-selectin. P-selectin-mediated adhesion is an important factor in the development of early atherosclerotic lesions.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight84.92 kDa
Note仅供科研使用

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