| Alias | NK1, CD57, HNK1, LEU7, NK 1, GLCATP, GLCUATP, beta 1, 3 glucuronyltransferase 1 |
| Catalog Number | KMH220 |
| Molecular Name | B3GAT1 |
| Species | Human |
| Host | Mammalian cells |
| Size | 50ug, 100ug |
| Protein Family | CD molecule |
| Purity | ≥90% as determined by SDS-PAGE |
| Purification | Affinity Purification |
| Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
| Formulation | PBS |
| Background | B3gat1 is a keyenzyme involved in human natural killer-1 (HNK-1) epitope synthesis. It addsa glucuronic residue to the terminal lactosamine residue (Galβ1-4GlcNAc-) ofa glycoprotein or glycolipid, which can be further sulfated to become the HNK1 epitope, a unique trisaccharide structure, HSO3-3GlcAβ1-3Galβ1-4GlcNAc-.The enzyme activity was found to be enhanced in the presence of sphingomyelinand phosphatidylinositol.The B3gat1 carbohydrate epitope ischaracteristically expressed on a series of cell adhesion molecules in additionto some glycolipids in the extracellular matrix and on the cell surface inthe nervous system, where it is involved in cell-cell and cellsubstratum interactionand recognition during the development of the nervous system. |
| Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Molecular Weight | 33.88 kDa |
| Note | 仅供科研使用 |
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