Recombinant Human CD39/ENTPD1 Protein, His Tag_天津卡梅德科技发展有限公司

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Recombinant Human CD39/ENTPD1 Protein, His Tag

Recombinant Human CD39/ENTPD1 Protein, His Tag

产品编号

KMH194

别名

CD39, SPG64, ATPDase, NTPDase 1, ENTPD1, ectonucleoside triphosphate diphosphohydrolase 1

规格

50ug
100ug

DATASHEET MSDS

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产品介绍

Alias	CD39, SPG64, ATPDase, NTPDase 1, ENTPD1, ectonucleoside triphosphate diphosphohydrolase 1
Catalog Number	KMH194
Molecular Name	ENTPD1
Species	Human
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	CD molecule
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	CD39, also known as ENTPD1, is a member of the GDA1/CD39 NTPase family. CD39 is weakly expressed on granulocytes while expressed highly on activated lymphoid cells. Human CD39 is found on most mature B cells, activated NK cells and activated T cells. In the nervous system, CD39 could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. It could also be implicated in the prevention of platelet aggregation and hydrolyzes ATP and ADP equally well. By hydrolyzing ATP and ADP, CD39 regulates vascular inflammation and thrombosis. It is the dominant ecto nucleotidase of vascular and placental trophoblastic tissues and appears to modulate the functional expression of type 2 purinergic (P2) G protein coupled receptors (GPCRs). CD39 transgenic mice exhibit impaired platelet aggregation, prolonged bleeding times, and resistance to systemic thromboembolism.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	48.62 kDa
Note	仅供科研使用

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