Recombinant Human CD33 Protein, His Tag_天津卡梅德科技发展有限公司

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Recombinant Human CD33 Protein, His Tag

Recombinant Human CD33 Protein, His Tag

产品编号

KMH188

别名

p67, SIGLEC3, SIGLEC 3, CD33 molecule

规格

50ug
100ug

DATASHEET MSDS

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产品介绍

Alias	p67, SIGLEC3, SIGLEC 3, CD33 molecule
Catalog Number	KMH188
Molecular Name	CD33
Species	Human
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	CD molecule
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	Myeloid cell surface antigen CD33 also known as SIGLEC3, Siglecs (sialic acid binding Ig-like lectins) and GP67, is a single-pass type I membrane protein which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. Human CD33/Siglec-3 cDNA encodes a 364 amino acid (aa) polypeptide with a hydrophobic signal peptide, an N-terminal Ig-like V-type domain, one Ig-like C2-type domains, a transmembrane region and a cytoplasmic tail. CD33/Siglec-3 usually considered myeloid-specific, but it can also be found on some lymphoid cells. In the immune response, CD33/Siglec-3 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. CD33/Siglec-3 induces apoptosis in acute myeloid leukemia.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	28.71 kDa
Note	仅供科研使用

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