Recombinant Human CD31 Protein, His Tag
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产品编号
KMH186
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别名
CD31, PECA1, GPIIA', PECAM 1, endoCAM, CD31/EndoCAM, platelet and endothelial cell adhesion molecule 1
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规格
- 50ug
- 100ug
Alias | CD31, PECA1, GPIIA', PECAM 1, endoCAM, CD31/EndoCAM, platelet and endothelial cell adhesion molecule 1 |
Catalog Number | KMH186 |
Molecular Name | PECAM1 |
Species | Human |
Host | Mammalian cells |
Size | 50ug, 100ug |
Protein Family | CD molecule |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Formulation | PBS |
Background | The CD31 adhesion molecule, also known as PECAM-1, is expressed in large amounts on endothelial cells at intercellular junctions and on T-cell subsets, and to a lesser extent on platelets and most other leukocytes such as monocytes and neutrophils. CD31 binds to itself homotypically, and also to the leukocyte integrinαvβ3 heterotypically. CD31 is required for the transendothelial migration of leukocytes through intercellular junctions of vascular endothelial cells. CD31 has been found in human plasma, and the presence of this circulating isoform is suggested to modulate the transendothelial migration of leukocytes.A DNA sequence encoding the extracellular domain (Met 1- Lys 61 ) of human CD31 (NP_433.3) precursor was expressed with the fused Fc region of human IgG1 at the C-terminus. |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 66.33 kDa |
Note | 仅供科研使用 |