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Recombinant Human CD31 Protein, His Tag

Recombinant Human CD31 Protein, His Tag

产品编号

KMH186

别名

CD31, PECA1, GPIIA', PECAM 1, endoCAM, CD31/EndoCAM, platelet and endothelial cell adhesion molecule 1

规格
  • 50ug
  • 100ug
产品介绍
AliasCD31, PECA1, GPIIA', PECAM 1, endoCAM, CD31/EndoCAM, platelet and endothelial cell adhesion molecule 1
Catalog NumberKMH186
Molecular NamePECAM1
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyCD molecule
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundThe CD31 adhesion molecule, also known as PECAM-1, is expressed in large amounts on endothelial cells at intercellular junctions and on T-cell subsets, and to a lesser extent on platelets and most other leukocytes such as monocytes and neutrophils. CD31 binds to itself homotypically, and also to the leukocyte integrinαvβ3 heterotypically. CD31 is required for the transendothelial migration of leukocytes through intercellular junctions of vascular endothelial cells. CD31 has been found in human plasma, and the presence of this circulating isoform is suggested to modulate the transendothelial migration of leukocytes.A DNA sequence encoding the extracellular domain (Met 1- Lys 61 ) of human CD31 (NP_433.3) precursor was expressed with the fused Fc region of human IgG1 at the C-terminus.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight66.33 kDa
Note仅供科研使用

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