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Recombinant Human CD30 Protein, His Tag

Recombinant Human CD30 Protein, His Tag

产品编号

KMH185

别名

CD30, Ki 1, D1S166E, TNFRSF8, TNF receptor superfamily member 8

规格
  • 50ug
  • 100ug
产品介绍
AliasCD30, Ki 1, D1S166E, TNFRSF8, TNF receptor superfamily member 8
Catalog NumberKMH185
Molecular NameTNFRSF8
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyCD molecule
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundCD3/TNFRSF8, a type I transmembrane glycoprotein belonging to the TNF receptor superfamily and tumor marker. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. It is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. CD3 is associated with anaplastic large cell lymphoma. It is expressed in embryonal carcinoma but not in seminoma and is thus is a useful marker in distinguishing between these germ cell tumors.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight41.8 kDa
Note仅供科研使用

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