Recombinant Human IL8/CXCL8 Protein, Fc Tag
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产品编号
KMH119
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别名
IL8, NAF, GCP1, LECT, LUCT, NAP1, GCP 1, LYNAP, MDNCF, MONAP, NAP 1, SCYB8, C X C motif chemokine ligand 8
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规格
- 50ug
- 100ug
Alias | IL8, NAF, GCP1, LECT, LUCT, NAP1, GCP 1, LYNAP, MDNCF, MONAP, NAP 1, SCYB8, C X C motif chemokine ligand 8 |
Catalog Number | KMH119 |
Molecular Name | CXCL8 |
Species | Human |
Host | Mammalian cells |
Size | 50ug, 100ug |
Protein Family | Interleukin |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Formulation | PBS, pH7.5 |
Background | IL-8 is a member of the alpha (CXC) subfamily of chemokines, which also includes platelet factor 4, GRO, IP1, etc. IL-8 is a potent chemoattractant for neutrophils. In addition, IL-8 also has a wide range of other proinflammatory effects. IL-8 causes degranulation of neutrophil specific granules and azurophilic granules. IL-8 induces expression of the cell adhesion molecules CD11/CD18 and enhances the adherence of neutrophils to endothelial cells and subendothelial matrix proteins. Besides neutrophils, IL-8 is also chemotactic for basophils, T cells and eosinophils. IL-8 has been reported to be a comitogen for keratinocytes and was also shown to be an autocrine growth factor for melanoma cells. IL-8 was also reported to be angiogenic both in vivo and in vitro. |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 33.58 kDa |
Note | 仅供科研使用 |