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Rhesus Macaque CD357 Protein, mFc Tag

Rhesus Macaque CD357 Protein, mFc Tag

产品编号

KMP2433

别名

肿瘤坏死因子受体超家族成员 18, Tumor necrosis factor receptor superfamily member 18, CD357

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias肿瘤坏死因子受体超家族成员 18, Tumor necrosis factor receptor superfamily member 18, CD357
Catalog NumberKMP2433
Product DescriptionThe Rhesus Macaque CD357 Protein(KMP2433) is produced in HEK293 Cells and the target gene encoding Met1-Asn343 is expressed with a 6His tag at the C-terminus.
Molecular NameCD357
SpeciesRhesus Macaque
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundTumor necrosis factor receptor superfamily member 18(Gitr) contains 3 TNFR-Cys repeats and it have four isforms.IsformA、isformB and isformC is single-pass type I membrane protein and isformD is a secreted protein. The protein is the receptor for TNFSF18.It seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. It mediated NF-kappa-B activation via the TRAF2/NIK pathway.It binds to TRAF1, TRAF2, and TRAF3, but not TRAF5 and TRAF6 and binds through its C-terminus to SIVA1/SIVA.It preferentially expressed in activated T lymphocytes and up-regulated in peripherical mononuclear cells after antigen stimulation/lymphocyte activation.
Predicted Molecular Weight38.39 kDa
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
Uniprot IDA0A2K5UCD9

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