Rhesus Macaque CD357 Protein, mFc Tag
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产品编号
KMP2433
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别名
肿瘤坏死因子受体超家族成员 18, Tumor necrosis factor receptor superfamily member 18, CD357
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规格
- 50ug
- 100ug
- 200ug
Alias | 肿瘤坏死因子受体超家族成员 18, Tumor necrosis factor receptor superfamily member 18, CD357 |
Catalog Number | KMP2433 |
Product Description | The Rhesus Macaque CD357 Protein(KMP2433) is produced in HEK293 Cells and the target gene encoding Met1-Asn343 is expressed with a 6His tag at the C-terminus. |
Molecular Name | CD357 |
Species | Rhesus Macaque |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | Tumor necrosis factor receptor superfamily member 18(Gitr) contains 3 TNFR-Cys repeats and it have four isforms.IsformA、isformB and isformC is single-pass type I membrane protein and isformD is a secreted protein. The protein is the receptor for TNFSF18.It seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. It mediated NF-kappa-B activation via the TRAF2/NIK pathway.It binds to TRAF1, TRAF2, and TRAF3, but not TRAF5 and TRAF6 and binds through its C-terminus to SIVA1/SIVA.It preferentially expressed in activated T lymphocytes and up-regulated in peripherical mononuclear cells after antigen stimulation/lymphocyte activation. |
Predicted Molecular Weight | 38.39 kDa |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form. |
Uniprot ID | A0A2K5UCD9 |