Human VSTM3 Protein, His Tag_天津卡梅德科技发展有限公司

>>

>>

>>

>

Human VSTM3 Protein, His Tag

Human VSTM3 Protein, His Tag

产品编号

KMP2415

别名

具有免疫球蛋白和 ITIM 结构域的 T 细胞免疫受体, T-cell immunoreceptor with Ig and ITIM domains,, VSIG9

规格

50ug
100ug
200ug

DATASHEET MSDS

立即询价加入询价列表大包装定制

产品介绍

Alias	具有免疫球蛋白和 ITIM 结构域的 T 细胞免疫受体, T-cell immunoreceptor with Ig and ITIM domains,, VSIG9
Catalog Number	KMP2415
Product Description	The Human VSTM3 Protein(KMP2415) is produced in HEK293 Cells and the target gene encoding Met22-Pro141 is expressed with a 6His tag at the C-terminus.
Molecular Name	VSTM3
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	T cell immunoreceptor with Ig and ITIM domains(TIGIT) is a member of the CD28 family within the Ig superfamily of proteins. TIGIT is expressed on NK cells and subsets of activated, memory and regulatory T cells, and particularly on follicular helper T cells within secondary lymphoid organs. It binds to CD155 and Nectin-2 that appear on dendritic cells(DC) and endothelium. Ligation of TIGIT on T cells down-regulates TCR-mediated activation and subsequent proliferation, while NK cell TIGIT ligation blocks NK cell cytotoxicity. Through CD155 and Nectin-2, which also interact with DNAM-1/CD226 and CD96/Tactile, TIGIT is part of an interacting network of Ig superfamily members that may augment or oppose each other. In particular, TIGIT binding to CD155 can antagonize the effects of DNAM1.
SDS-PAGE
Predicted Molecular Weight	13.89 kDa
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
Uniprot ID	C9J0B0#structure

推荐产品

400-621-6806
614353794
周一至周五 9:00-18:00
0