Human CD137L Protein, His Tag_天津卡梅德科技发展有限公司

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Human CD137L Protein, His Tag

Human CD137L Protein, His Tag

产品编号

KMP2413

别名

肿瘤坏死因子配体超家族成员 9, CD137L, TNFSF9

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	肿瘤坏死因子配体超家族成员 9, CD137L, TNFSF9
Catalog Number	KMP2413
Product Description	The Human CD137L Protein(KMP2413) is produced in E.coli and the target gene encoding Arg71-Glu254 is expressed with a 6His tag at the C-terminus.
Molecular Name	CD137L
Species	Human
Host	E. coli
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	20mM TrisHCl, 150mM NaCl, pH7.4
Background	Tumor necrosis factor ligand superfamily member 9(4-1BBL) is single-pass type II membrane protein which is a member of the the tumor necrosis factor family. 4-1BBL is a 254 amino acids cytokine that is expressed in brain, placenta, lung, skeletal muscle and kidney. TNFSF9 has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine may have a role in activation-induced cell death(AICD) and cognate interactions between T-cells and B-cells/macrophages. It has also been shown to be required for the optimal CD8 responses in CD8 T cells, and is thought to be involved in T cell-tumor cell interaction.
SDS-PAGE
Predicted Molecular Weight	20.9 kDa
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
Uniprot ID	P41273
References	J. Biol. Chem. 285:9202-9210 (2010)
Function	Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.

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