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Human CD27 Protein, Fc Tag, His Tag

Human CD27 Protein, Fc Tag, His Tag

产品编号

KMP2411

别名

肿瘤坏死因子受体超家族成员 7, CD27 antigen, CD27L receptor, T-cell activation antigen CD27

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias肿瘤坏死因子受体超家族成员 7, CD27 antigen, CD27L receptor, T-cell activation antigen CD27
Catalog NumberKMP2411
Product DescriptionThe Human CD27 Protein(KMP2411) is produced in HEK293 Cells and the target gene encoding Thr21-Ile192 is expressed with a Fc, 6His tag at the C-terminus.
Molecular NameCD27
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
Formulation20mM Tris, 150mM NaCl, pH8.0
BackgroundCD27 antigen is also known as CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor superfamily member 7, T14 and TNFRSF7. In humans, it is encoded by the CD27 gene. CD27 is a single-pass type I membrane protein with 3 TNFR-Cys repeats. It is a member of the TNF-receptor superfamily and is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. It plays a role in survival of activated T-cells and apoptosis through association with SIVA1.
Predicted Molecular Weight20.08 kDa
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
Uniprot IDP26842
FunctionReceptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.

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