Human CD40L Receptor Protein, His Tag_天津卡梅德科技发展有限公司

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Human CD40L Receptor Protein, His Tag

Human CD40L Receptor Protein, His Tag

产品编号

KMP2402

别名

肿瘤坏死因子受体超家族成员 5, Tumor Necrosis Factor Receptor Superfamily member 5, CD40L

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	肿瘤坏死因子受体超家族成员 5, Tumor Necrosis Factor Receptor Superfamily member 5, CD40L
Catalog Number	KMP2402
Product Description	The Human CD40L Receptor Protein(KMP2402) is produced in HEK293 Cells and the target gene encoding Glu21-Arg193 is expressed with a 6His tag at the C-terminus.
Molecular Name	CD40
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	20mM PB, 150mM NaCl, pH7.4
Background	CD40 is a Type I Transmembrane Glycoprotein that belongs to the TNF Receptor Superfamily. CD40 is expressed in B cells, follicular dendritic cells, dendritic cells, activated monocytes, macrophages, endothelial cells, vascular smooth muscle cells, and several tumor cell lines. The extracellular domain of CD40 is characterized by Cysteine rich repeat regions. Interaction of CD40 with its ligand(CD40L) leads to aggregation of CD40 molecules, which in turn interact with cytoplasmic components to initiate signaling pathways. Several different TRAF proteins(adaptor proteins) have been identified to serves as mediators of the signal transduction. CD40 plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation.
SDS-PAGE
Predicted Molecular Weight	19.99 kDa
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
Uniprot ID	A0A8Q3SI60

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