Mouse CD80 Protein, Fc Tag_天津卡梅德科技发展有限公司

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Mouse CD80 Protein, Fc Tag

Mouse CD80 Protein, Fc Tag

产品编号

KMP2398

别名

T淋巴细胞活化抗原CD80, T-lymphocyte activation antigen CD80, Activation B7-1 antigen

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	T淋巴细胞活化抗原CD80, T-lymphocyte activation antigen CD80, Activation B7-1 antigen
Catalog Number	KMP2398
Product Description	The Mouse CD80 Protein(KMP2398) is produced in HEK293 Cells and the target gene encoding Val38-Lys245 is expressed with a Fc tag at the C-terminus.
Molecular Name	CD80
Species	Mouse
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4. Studies have shown that CTLA-4 binds mostly to CD80. The structure presents two extracellular domains: a membrane distal variable-like domain(IgV) and a membrane proximal Ig constant-like domain(IgC) along with an intracellular domain. Both IgV and IgC consist of anti-parallel beta sandwiches joined by a short linker region. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells.
SDS-PAGE
Predicted Molecular Weight	23.69 kDa
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
Uniprot ID	Q3U4B5

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