Human CD275 Protein, His Tag_天津卡梅德科技发展有限公司

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Human CD275 Protein, His Tag

Human CD275 Protein, His Tag

产品编号

KMP2394

别名

诱导性T细胞促刺激配体, B7 homolog 2, B7-H2

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	诱导性T细胞促刺激配体, B7 homolog 2, B7-H2
Catalog Number	KMP2394
Product Description	The Human CD275 Protein(KMP2394) is produced in HEK293 Cells and the target gene encoding Asp19-Ser258 is expressed with a 6His tag at the C-terminus.
Molecular Name	CD275
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	20mM PB, 150mM NaCl, 1mM EDTA, pH7.2
Background	Inducible Co-Stimulator Ligand(ICOSLG) belongs to the immunoglobulin superfamily. ICOSLG contains Ig-like C2-type(immunoglobulin-like) domain and 1 Ig-like V-type(immunoglobulin-like) domain. ICOSLG acts as a costimulatory signal for T-cell proliferation and cytokine secretion, it also induces B-cell proliferation and differentiation into plasma cells. It could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function. ICOSLG is widely expressed lymph nodes, leukocytes and spleen, detected on activated monocytes and dendritic cells.
SDS-PAGE
Predicted Molecular Weight	27.51 kDa
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
Uniprot ID	O75144
Function	Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity).

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