Human Gi24 Protein, Fc Tag_天津卡梅德科技发展有限公司

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Human Gi24 Protein, Fc Tag

Human Gi24 Protein, Fc Tag

产品编号

KMP2392

别名

V 集免疫调节受体, Platelet receptor Gi24, Gi24

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	V 集免疫调节受体, Platelet receptor Gi24, Gi24
Catalog Number	KMP2392
Product Description	The Human Gi24 Protein(KMP2392) is produced in HEK293 Cells and the target gene encoding Phe33-Ala194 is expressed with a Fc tag at the C-terminus.
Molecular Name	Gi24
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	platelet receptor Gi24 is a single-pass type I membrane protein, and located at the cell surface. The protein can be cleaved by MMP14, and stimulate MMP14-mediated MMP2 activation. It is participated in the BMP signaling pathway. It also regulates the CD4-pasitive, alpha-beta T cell proliferation, and T cell cytokine production negatively. However, the protein can regulate stem cell differentiation positively.
SDS-PAGE
Predicted Molecular Weight	18.14 kDa
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
Uniprot ID	Q9H7M9
References	1.Cancer Sci. 101:2368-2374 (2010) 2.Cancer Res. 74:1924-1932 (2014)
Function	Immunoregulatory receptor which inhibits the T-cell response (PubMed:24691993). May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (By similarity). May stimulate MMP14-mediated MMP2 activation (PubMed:20666777).

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