Human CD47 Protein, Fc Tag
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产品编号
KMP2379
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别名
整联蛋白相关蛋白, Leukocyte Surface Antigen CD47, MER6
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规格
- 50ug
- 100ug
- 200ug
Alias | 整联蛋白相关蛋白, Leukocyte Surface Antigen CD47, MER6 |
Catalog Number | KMP2379 |
Product Description | The Human CD47 Protein(KMP2379) is produced in HEK293 Cells and the target gene encoding Gln19-Pro139 is expressed with a Fc tag at the C-terminus. |
Molecular Name | CD47 |
Species | Human |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | CD47(Integrin-Associated Protein,IAP) is a 40 - 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes. |
SDS-PAGE | ![]() |
Predicted Molecular Weight | 13.73 kDa |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form. |
Uniprot ID | A0A2R8Y484#structure |