Mouse CD252 Protein, His Tag_天津卡梅德科技发展有限公司

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Mouse CD252 Protein, His Tag

Mouse CD252 Protein, His Tag

产品编号

KMP2351

别名

肿瘤坏死因子受体超家族成员 4, Tumor necrosis factor ligand superfamily member 4, OX40L

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	肿瘤坏死因子受体超家族成员 4, Tumor necrosis factor ligand superfamily member 4, OX40L
Catalog Number	KMP2351
Product Description	The Mouse CD252 Protein(KMP2351) is produced in HEK293 Cells and the target gene encoding Ser51-Leu198 is expressed with a 8His tag at the N-terminus.
Molecular Name	CD252
Species	Mouse
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	OX40 ligand(OX40L), also called CD252, is a single-pass type II membrane protein of the TNF/TNF receptor superfamily. OX40L is expressed by DCs, macrophages and B cells and signals via its cognate receptor OX40 which is mainly expressed on APCs. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells. OX40L–OX40 co-stimulation leads to activation of TNF receptor associated factor(TRAF) 2, 3 and 5. This pathway has been shown to prolong the survival of effector CD4+Th cells as well as contributes to generation of memory T cells.
SDS-PAGE
Predicted Molecular Weight	17.46 kDa
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
Uniprot ID	P43488
Function	Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production.

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