Mouse CD27 Protein, Fc Tag, His Tag_天津卡梅德科技发展有限公司

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Mouse CD27 Protein, Fc Tag, His Tag

Mouse CD27 Protein, Fc Tag, His Tag

产品编号

KMP2335

别名

肿瘤坏死因子受体超家族成员 7, CD27 antigen, CD27L receptor, T-cell activation antigen CD27

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	肿瘤坏死因子受体超家族成员 7, CD27 antigen, CD27L receptor, T-cell activation antigen CD27
Catalog Number	KMP2335
Product Description	The Mouse CD27 Protein(KMP2335) is produced in HEK293 Cells and the target gene encoding Pro24-Arg182 is expressed with a Fc, 6His tag at the C-terminus.
Molecular Name	CD27
Species	Mouse
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Mouse CD27 is a single-pass type I membrane protein which is a member of the tumor necrosis factor receptor superfamily. CD27 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. CD27 transduces signals that lead to the activation of NF-κB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein(SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Predicted Molecular Weight	18.62 kDa
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
Uniprot ID	P41272
Function	Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.

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