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Rhesus Macaque CD86 Protein, His Tag

Rhesus Macaque CD86 Protein, His Tag

产品编号

KMP2298

别名

T 淋巴细胞活化抗原 CD86, T-lymphocyte activation antigen CD86, CD86

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
AliasT 淋巴细胞活化抗原 CD86, T-lymphocyte activation antigen CD86, CD86
Catalog NumberKMP2298
Product DescriptionThe Rhesus Macaque CD86 Protein(KMP2298) is produced in HEK293 Cells and the target gene encoding Tyr31-Pro247 is expressed with a 6His tag at the C-terminus.
Molecular NameCD86
SpeciesRhesus Macaque
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundT-lymphocyte activation antigen CD86(B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. It is highly expressed on activated antigen presenting cells. CD86 involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. It is expressed by activated B-lymphocytes and monocytes and promoted by MARCH8 and results in endocytosis and lysosomal degradation.
SDS-PAGE
Predicted Molecular Weight24.53 kDa
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
Uniprot IDH9ZFI8

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