| Alias | 含 V 组结构域的 T 细胞激活抑制剂 1, T cell costimulatory molecule B7x, VTCN1 |
| Catalog Number | KMP2293 |
| Product Description | The Rhesus Macaque VTCN1 Protein(KMP2293) is produced in HEK293 Cells and the target gene encoding Phe29-Ala258 is expressed. |
| Molecular Name | VTCN1 |
| Species | Rhesus Macaque |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >95% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | B7 Homolog 4(B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells(Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. It also involved in promoting epithelial cell transformation. |
| SDS-PAGE |  |
| Predicted Molecular Weight | 25.3 kDa |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form. |
| Uniprot ID | F7B770 |
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