Human CD252 Protein, mFc Tag
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产品编号
KMP2279
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别名
肿瘤坏死因子受体超家族成员 4, Tumor necrosis factor ligand superfamily member 4, OX40L
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规格
- 50ug
- 100ug
- 200ug
Alias | 肿瘤坏死因子受体超家族成员 4, Tumor necrosis factor ligand superfamily member 4, OX40L |
Catalog Number | KMP2279 |
Product Description | The Human CD252 Protein(KMP2279) is produced in HEK293 Cells and the target gene encoding Gln51-Leu183 is expressed with a mFc tag at the C-terminus. |
Molecular Name | CD252 |
Species | Human |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein.OX40L is expressed on the surface of activated B cells, T cells, dendritic cells and endothelial cells. OX40L binds to OX40(CD134), a member of the TNF receptor superfamily that is expressed predominantly on activated CD4+ T cells. OX40-OX40L co-stimulates signal to promote the survival and proliferation of activated CD4+ T cells and prolong the immune response. It involved in T-cell proliferation and cytokine production. Additional, it has been found association with systemic lupus erythematosus, no association with occurrence of atherosclerosis. |
SDS-PAGE | ![]() |
Predicted Molecular Weight | 15.43 kDa |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form. |
Uniprot ID | P23510 |
Function | Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production. |