Human Biotinylated Mesothelin Protein, His Tag, Avi Tag_天津卡梅德科技发展有限公司

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Human Biotinylated Mesothelin Protein, His Tag, Avi Tag

Human Biotinylated Mesothelin Protein, His Tag, Avi Tag

产品编号

KMP2274

别名

间皮素, Megakaryocyte potentiating facto, Mesothelin

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	间皮素, Megakaryocyte potentiating facto, Mesothelin
Catalog Number	KMP2274
Product Description	The Human Biotinylated Mesothelin Protein(KMP2274) is produced in HEK293 Cells and the target gene encoding Glu296-Ser598 is expressed with a 6His, Avi tag at the C-terminus.
Molecular Name	Mesothelin
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Mesothelin is a cell surface glycoprotein whose expression is limited to mesothelial cells of the serosa(pleura, pericardium, and peritoneum) and epithelial cells of the trachea, tonsils, fallopian tube, and kidneys. Mesothelin plays an important role in cell survival, proliferation, migration, invasion, tumor progression, and resistance to chemotherapy. The overexpression of mesothelin can activate NF-κB and signal transducer and activator of transcription 3(Stat3), inhibit apoptotic signaling and TNF-α-induced apoptosis, and accelerate the G1–S transition. Mesothelin is also found overexpressed in various cancers, including malignant mesothelioma, pancreatic or ovarian carcinoma, sarcomas and in some gastrointestinal or pulmonary carcinomas. As a result of its limited expression in normal tissues, mesothelin has been reported as an ideal tumor-associated marker for the development of targeted therapy.
SDS-PAGE
Predicted Molecular Weight	33.99 kDa
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
Uniprot ID	H3BR90

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