Human CD30 Protein, His Tag, Avi Tag_天津卡梅德科技发展有限公司

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Human CD30 Protein, His Tag, Avi Tag

Human CD30 Protein, His Tag, Avi Tag

产品编号

KMP2273

别名

肿瘤坏死因子受体8, Tumor necrosis factor receptor superfamily member 8, CD30

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	肿瘤坏死因子受体8, Tumor necrosis factor receptor superfamily member 8, CD30
Catalog Number	KMP2273
Product Description	The Human CD30 Protein(KMP2273) is produced in HEK293 Cells and the target gene encoding Phe19-Lys379 is expressed with a 6His, Avi tag at the C-terminus.
Molecular Name	CD30
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	20mM PB, 150mM NaCl, pH7.4
Background	CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody responses. CD30 is expressed by activated, but not by resting, T and B cells. Aberrant expression of CD30 by mastocytosis mast cells and interaction with its ligand CD30L(CD153) appears to play an important role in the pathogenesis and clinical presentation of systemic mastocytosis. CD30 has been considered as a specific diagnostic biomarker of anaplastic large cell lymphoma(ALCL) and classical Hodgkin lymphoma(cHL). CD30 is also a biomarker used for targeted therapy by an antibody–drug conjugate.
SDS-PAGE
Predicted Molecular Weight	39.25 kDa
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
Uniprot ID	P28908
References	1.Cell 73:1349-1360 (1993) 2.J. Biol. Chem. 272:2042-2045 (1997)
Function	Receptor for TNFSF8/CD30L . May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B .

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