Human 5T4 Protein, Avi Tag, His Tag_天津卡梅德科技发展有限公司

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Human 5T4 Protein, Avi Tag, His Tag

Human 5T4 Protein, Avi Tag, His Tag

产品编号

KMP2244

别名

滋养层糖蛋白, Human M6P1 Protein, 5T4

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	滋养层糖蛋白, Human M6P1 Protein, 5T4
Catalog Number	KMP2244
Product Description	The Human 5T4 Protein(KMP2244) is produced in HEK293 Cells and the target gene encoding Ser32-Ser355 is expressed with a AVI, 6His tag at the C-terminus.
Molecular Name	5T4
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Trophoblast glycoprotein, also known as TPBG and 5T4, it belongs to the LRR family of proteins. The C-terminus of LRR N-terminal cap(LRRNT) and LRR 1 are essential for the inhibition of the Wnt signaling pathway. TPBG may function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. It expressed by all types of trophoblasts as early as 9 weeks of development. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.
SDS-PAGE
Predicted Molecular Weight	36.15 kDa
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
Uniprot ID	Q13641#structure
References	1 Dev. Cell 21:1129-1143 (2011)
Function	May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization.

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