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Rhesus CD28 Protein, His Tag, Avi Tag

Rhesus CD28 Protein, His Tag, Avi Tag

产品编号

KMP4367

别名

T细胞特异性表面糖蛋白CD28, CD28 Protein, Rhesus CD28 Protein, His Tag, Avi Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
AliasT细胞特异性表面糖蛋白CD28, CD28 Protein, Rhesus CD28 Protein, His Tag, Avi Tag
Catalog NumberKMP4367
Product DescriptionThe Rhesus CD28 Protein(KMP4367) is produced in HEK293 Cells. A DNA sequence encoding the Human/Cynomolgus/Rhesus CD28 (P10747-1) (Met1-Pro152) is expressed with a C-terminal polyhistidine tag followed by an Avi tag. The expressed protein is biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
Molecular NameCD28
SpeciesRhesus
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundCD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell response pathways. B7/CD28 family members, which can augment or antagonize T-cell receptor signaling, in the regulation of central and peripheral T-cell tolerance. CD28 is thus involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight18.40 kDa

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