Rhesus c-MET Protein, His Tag_天津卡梅德科技发展有限公司

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Rhesus c-MET Protein, His Tag

Rhesus c-MET Protein, His Tag

产品编号

KMP4357

别名

细胞间质上皮转换因子, c-MET Protein, Rhesus c-MET Protein, His Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	细胞间质上皮转换因子, c-MET Protein, Rhesus c-MET Protein, His Tag
Catalog Number	KMP4357
Product Description	The Rhesus c-MET Protein(KMP4357) is produced in HEK293 Cells. A DNA sequence encoding the Cynomolgus/Rhesus MET (A0A2K5UM36-1/NP_001162100.2) (Met1-Thr932) is expressed with a polyhistidine tag at the C-terminus. Cynomolgus and Rhesus MET sequences are identical. The purified protein is biotinylated in vitro.
Molecular Name	c-MET
Species	Rhesus
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR protein is produced as a single-chain precursor, and HGF is the only known ligand. Normal HGF/HGFR signaling is essential for embryonic development, tissue repair, or wound healing, whereas aberrantly active HGFR has been strongly implicated in tumorigenesis, particularly in the development of invasive and metastatic phenotypes. HGFR protein is a multifaceted regulator of growth, motility, and invasion, and is normally expressed by cells of epithelial origin. Preclinical studies suggest that targeting aberrant HGFR signaling could be an attractive therapy in cancer.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	103.1 kDa

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