Rhesus CD84 Protein, His Tag_天津卡梅德科技发展有限公司

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Rhesus CD84 Protein, His Tag

Rhesus CD84 Protein, His Tag

产品编号

KMP4350

别名

白细胞分化抗原CD84, CD84 Protein, Rhesus CD84 Protein, His Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	白细胞分化抗原CD84, CD84 Protein, Rhesus CD84 Protein, His Tag
Catalog Number	KMP4350
Product Description	The Rhesus CD84 Protein(KMP4350) is produced in HEK293 Cells. A DNA sequence encoding the Cynomolgus/Rhesus CD84 (XP_005541302.1) (Met1-Arg220) is expressed with a polyhistidine tag at the C-terminus. Cynomolgus and Rhesus CD84 sequences are identical.
Molecular Name	CD84
Species	Rhesus
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	The CD2 family receptors are type I transmembrane glycoproteins belonging to immunoglobulin (Ig) superfamily characterized by a membrane-proximal Ig constant 2 (C2) domain and a membrane-distal variable (V) domain that is responsible for ligand recognition. CD84, also known as LY9B and SLAMF5, is a homophilic member of the SLAM (signaling lymphocyte activation molecule) subfamily of the CD2 family. The SLAM family receptorsmediate signal transduction through the interaction of its ITSM (immunoreceptor tyrosine-based switch motifs) in the intracellular region and the SH2 domain of adaptor molecules SAP (SLAM-associated protein) and EAT-2 (EWS-activated transcript 2), and accordingly modulate both adaptive and innate immune responses. The CD84-CD84 interaction was independent of its cytoplasmic tail. Thus, CD84 is its own ligand and acts as a costimulatory molecule. CD84 is expressed on cells from almost all hematopoietic lineages and on CD34+ hematopoietic progenitor cells, suggesting that CD84 serves as a marker for committed hematopoietic progenitor cells.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	23.6 kDa

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