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Rhesus TIE2 Protein, His Tag

Rhesus TIE2 Protein, His Tag

产品编号

KMP4326

别名

TEK受体酪氨酸激酶, TIE2 Protein, Rhesus TIE2 Protein, His Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
AliasTEK受体酪氨酸激酶, TIE2 Protein, Rhesus TIE2 Protein, His Tag
Catalog NumberKMP4326
Product DescriptionThe Rhesus TIE2 Protein(KMP4326) is produced in HEK293 Cells. A DNA sequence encoding the Rhesus TEK (XP_001105270.1) (Met1-Lys745) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameTIE2
SpeciesRhesus
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundTEK, or TIE-2, is an endothelial cell-specific receptor tyrosine kinase (RTK) that is known as a functioning molecule of vascular endothelial cells. TEK comprises a subfamily of RTK with TIE, and these two receptors play critical roles in vascular maturation, maintenance of integrity and remodeling. Targeted mutagenesis of both Tek and its agonistic ligand, Angiopoietin-1, result in embryonic lethality, demonstrating that the signal transduction pathways mediated by this receptor are crucial for normal embryonic development. TEK signaling is indispensable for the development of the embryonic vasculature and suggests that TEK signaling may also be required for the development of the tumor vasculature.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight84.2 kDa

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