Rhesus BTLA Protein, His Tag
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产品编号
KMP4323
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别名
B和T淋巴细胞衰减因子, BTLA Protein, Rhesus BTLA Protein, His Tag
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规格
- 50ug
- 100ug
- 200ug
Alias | B和T淋巴细胞衰减因子, BTLA Protein, Rhesus BTLA Protein, His Tag |
Catalog Number | KMP4323 |
Product Description | The Rhesus BTLA Protein(KMP4323) is produced in HEK293 Cells. A DNA sequence encoding the BTLA (EHH16054.1) (Met1-Leu155) is expressed with a polyhistidine tag at the C-terminus. |
Molecular Name | BTLA |
Species | Rhesus |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >85% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeutic promise. BTLA is crucial to understand the mechanism(s) of action of these antibodies before attempting clinical applications. BTLA is not expressed by naive T cells, but it is induced during activation and remains expressed on T helper type 1 (T(H)1) but not T(H)2 cells. BTLA is a third inhibitory receptor on T lymphocytes with similarities to cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and programmed death 1 (PD-1). |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 19.3 kDa |