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Rhesus Semaphorin 4D Protein, His Tag

Rhesus Semaphorin 4D Protein, His Tag

产品编号

KMP4314

别名

信号素4D, Semaphorin 4D Protein, Rhesus Semaphorin 4D Protein, His Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias信号素4D, Semaphorin 4D Protein, Rhesus Semaphorin 4D Protein, His Tag
Catalog NumberKMP4314
Product DescriptionThe Rhesus Semaphorin 4D Protein(KMP4314) is produced in HEK293 Cells. A DNA sequence encoding the Rhesus SEMA4D (EHH24221.1) (Met1-Arg734) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameSemaphorin 4D
SpeciesRhesus
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundSemaphorin 4D (SEMA4D or CD100) is a member of the semaphorin family of proteins and an important mediator of the movement and differentiation of multiple cell types, including those of the immune, vascular, and nervous systems. VEGF and SEMA4D had a positive correlation with the malignant degree of ovarian cancer, and SEMA4D can serve as an independent prognostic factor. SEMA4D was the first semaphorin described to have immune functions and serves important roles in T cell priming, antibody production, and cell-to-cell adhesion. Proteolytic cleavage of SEMA4D from the cell surface gives rise to a soluble fragment of SEMA4D (sSEMA4D). Similar to the transmembranal form, sSEMA4D is thought to have immunoregulatory properties.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight80.7 kDa

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