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Rhesus IL17RA Protein, His Tag

Rhesus IL17RA Protein, His Tag

产品编号

KMP4302

别名

白介素17受体A, IL17RA Protein, Rhesus IL17RA Protein, His Tag

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias白介素17受体A, IL17RA Protein, Rhesus IL17RA Protein, His Tag
Catalog NumberKMP4302
Product DescriptionThe Rhesus IL17RA Protein(KMP4302) is produced in HEK293 Cells. A DNA sequence encoding the Rhesus IL17RA (XP_001102483.2) (Met1-Trp320) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameIL17RA
SpeciesRhesus
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundInterleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor that binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17R/IL-17RA (CD217) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor IL-17RA play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Defects in IL-17R/IL-17RA (CD217) are the cause of familial candidiasis type 5 (CANDF5). CANDF5 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails, and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight35.6 kDa

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